Recombinant IGF-1 Induces Sex-Specific Changes in Bone Composition and Remodeling in Adult Mice with Pappa2 Deficiency

Deficiency of pregnancy-associated plasma protein-A2 (PAPP-A2), an IGF-1 availability regulator, causes postnatal growth failure and dysregulation of bone size and density. The present study aimed to determine the effects of recombinant murine IGF-1 (rmIGF-1) on bone composition and remodeling in co...

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Detalles Bibliográficos
Autores principales: Rubio, Leticia, Vargas, Antonio, Rivera, Patricia, López-Gambero, Antonio J., Tovar, Rubén, Christians, Julian K., Martín-de-las-Heras, Stella, Rodríguez de Fonseca, Fernando, Chowen, Julie A., Argente, Jesús, Suárez, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070906/
https://www.ncbi.nlm.nih.gov/pubmed/33919940
http://dx.doi.org/10.3390/ijms22084048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070906/
https://www.ncbi.nlm.nih.gov/pubmed/33919940
http://dx.doi.org/10.3390/ijms22084048

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