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Synergistic Effect of Doxorubicin and siRNA-Mediated Silencing of Mcl-1 Using Cationic Niosomes against 3D MCF-7 Spheroids

Chemotherapy is a vital option for cancer treatment; however, its therapeutic outcomes are limited by dose-dependent toxicity and the occurrence of chemoresistance. siRNAs have emerged as an attractive therapeutic option enabling specific interference with target genes. Combination therapy using che...

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Detalles Bibliográficos
Autores principales: Pengnam, Supusson, Plianwong, Samarwadee, Patrojanasophon, Prasopchai, Radchatawedchakoon, Widchaya, Yingyongnarongkul, Boon-ek, Opanasopit, Praneet, Charoensuksai, Purin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070967/
https://www.ncbi.nlm.nih.gov/pubmed/33919902
http://dx.doi.org/10.3390/pharmaceutics13040550