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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer
SIMPLE SUMMARY: The antimalarial drug artesunate also has anticancer activity. Based on what is known about how artesunate works in malaria, we hypothesized that the kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway, which is often mutated in non-...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070990/ https://www.ncbi.nlm.nih.gov/pubmed/33920029 http://dx.doi.org/10.3390/cancers13081885 |