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Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation

Antibiotic resistance is spreading worldwide and it has become one of the most important issues in modern medicine. In this context, the bacterial RNA degradation and processing machinery are essential processes for bacterial viability that may be exploited for antimicrobial therapy. In Staphylococc...

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Detalles Bibliográficos
Autores principales: Suigo, Lorenzo, Chojnacki, Michaelle, Zanotto, Carlo, Sebastián-Pérez, Victor, Morghen, Carlo De Giuli, Casiraghi, Andrea, Dunman, Paul M., Valoti, Ermanno, Straniero, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071009/
https://www.ncbi.nlm.nih.gov/pubmed/33920000
http://dx.doi.org/10.3390/antibiotics10040438