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Predicting TCR-Epitope Binding Specificity Using Deep Metric Learning and Multimodal Learning

Understanding the recognition of specific epitopes by cytotoxic T cells is a central problem in immunology. Although predicting binding between peptides and the class I Major Histocompatibility Complex (MHC) has had success, predicting interactions between T cell receptors (TCRs) and MHC class I-pep...

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Detalles Bibliográficos
Autores principales: Luu, Alan M., Leistico, Jacob R., Miller, Tim, Kim, Somang, Song, Jun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071129/
https://www.ncbi.nlm.nih.gov/pubmed/33920780
http://dx.doi.org/10.3390/genes12040572