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Predicting TCR-Epitope Binding Specificity Using Deep Metric Learning and Multimodal Learning
Understanding the recognition of specific epitopes by cytotoxic T cells is a central problem in immunology. Although predicting binding between peptides and the class I Major Histocompatibility Complex (MHC) has had success, predicting interactions between T cell receptors (TCRs) and MHC class I-pep...
Autores principales: | Luu, Alan M., Leistico, Jacob R., Miller, Tim, Kim, Somang, Song, Jun S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071129/ https://www.ncbi.nlm.nih.gov/pubmed/33920780 http://dx.doi.org/10.3390/genes12040572 |
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