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Antibacterial Mechanisms and Efficacy of Sarecycline in Animal Models of Infection and Inflammation

Prolonged broad-spectrum antibiotic use is more likely to induce bacterial resistance and dysbiosis of skin and gut microflora. First and second-generation tetracycline-class antibiotics have similar broad-spectrum antibacterial activity. Targeted tetracycline-class antibiotics are needed to limit a...

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Detalles Bibliográficos
Autores principales: Bunick, Christopher G., Keri, Jonette, Tanaka, S. Ken, Furey, Nika, Damiani, Giovanni, Johnson, Jodi L., Grada, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071131/
https://www.ncbi.nlm.nih.gov/pubmed/33920812
http://dx.doi.org/10.3390/antibiotics10040439