Behavior of Chemokine Receptor 6 (CXCR6) in Complex with CXCL16 Soluble form Chemokine by Molecular Dynamic Simulations: General Protein‒Ligand Interaction Model and 3D-QSAR Studies of Synthetic Antagonists

The CXCR6‒CXCL16 axis is involved in several pathological processes, and its overexpression has been detected in different types of cancer, such as prostate, breast, ovary, and lung cancer, along with schwannomas, in which it promotes invasion and metastasis. Moreover, this axis is involved in ather...

Descripción completa

Detalles Bibliográficos
Autores principales: Aguilera-Durán, Giovanny, Romo-Mancillas, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071165/
https://www.ncbi.nlm.nih.gov/pubmed/33920834
http://dx.doi.org/10.3390/life11040346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071165/
https://www.ncbi.nlm.nih.gov/pubmed/33920834
http://dx.doi.org/10.3390/life11040346

Ejemplares similares