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Hyperoxidation of Peroxiredoxins and Effects on Physiology of Drosophila

The catalytic activity of peroxiredoxins (Prx) is determined by the conserved peroxidatic cysteine (Cys(P)), which reacts with peroxides to form sulfenic acid (Cys-SOH). Under conditions of oxidative stress, Cys(P) is oxidized to catalytically inactive sulfinic (Cys-SO(2)) and sulfonic (Cys-SO(3)) f...

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Detalles Bibliográficos
Autores principales: McGinnis, Austin, Klichko, Vladimir I., Orr, William C., Radyuk, Svetlana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071185/
https://www.ncbi.nlm.nih.gov/pubmed/33920774
http://dx.doi.org/10.3390/antiox10040606