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Hyperoxidation of Peroxiredoxins and Effects on Physiology of Drosophila
The catalytic activity of peroxiredoxins (Prx) is determined by the conserved peroxidatic cysteine (Cys(P)), which reacts with peroxides to form sulfenic acid (Cys-SOH). Under conditions of oxidative stress, Cys(P) is oxidized to catalytically inactive sulfinic (Cys-SO(2)) and sulfonic (Cys-SO(3)) f...
Autores principales: | McGinnis, Austin, Klichko, Vladimir I., Orr, William C., Radyuk, Svetlana N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071185/ https://www.ncbi.nlm.nih.gov/pubmed/33920774 http://dx.doi.org/10.3390/antiox10040606 |
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