Transdermal System Based on Solid Cilostazol Nanoparticles Attenuates Ischemia/Reperfusion-Induced Brain Injury in Mice

Cilostazol (CIL) exerted a protective effect by promoting blood–brain barrier integrity as well as improving the status of neurological dysfunctions following cerebral ischemia/reperfusion (I/R) injury. We attempted to design a 0.5% CIL carbopol gel using solid nanoparticles (CIL-Ngel), and then inv...

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Detalles Bibliográficos
Autores principales: Otake, Hiroko, Yamaguchi, Mizuki, Ogata, Fumihiko, Deguchi, Saori, Yamamoto, Naoki, Sasaki, Hiroshi, Kawasaki, Naohito, Nagai, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071240/
https://www.ncbi.nlm.nih.gov/pubmed/33920878
http://dx.doi.org/10.3390/nano11041009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071240/
https://www.ncbi.nlm.nih.gov/pubmed/33920878
http://dx.doi.org/10.3390/nano11041009

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