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Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2–Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages

Mitocryptides are a novel family of endogenous neutrophil-activating peptides originating from various mitochondrial proteins. Mitocryptide-2 (MCT-2) is one of such neutrophil-activating peptides, and is produced as an N-formylated pentadecapeptide from mitochondrial cytochrome b. Although MCT-2 is...

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Detalles Bibliográficos
Autores principales: Marutani, Takayuki, Nishino, Kodai, Miyaji, Tomoyuki, Kamada, Keisuke, Ohura, Koji, Kiso, Yoshiaki, Mukai, Hidehito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071274/
https://www.ncbi.nlm.nih.gov/pubmed/33920954
http://dx.doi.org/10.3390/ijms22084084