Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket

Multidrug resistant Staphylococcus aureus is a severe threat, responsible for most of the nosocomial infections globally. This resistant strain is associated with a 64% increase in death compared to the antibiotic-susceptible strain. The prokaryotic protein FtsZ and the cell division cycle have been...

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Detalles Bibliográficos
Autores principales: Straniero, Valentina, Sebastián-Pérez, Victor, Suigo, Lorenzo, Margolin, William, Casiraghi, Andrea, Hrast, Martina, Zanotto, Carlo, Zdovc, Irena, Radaelli, Antonia, Valoti, Ermanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071314/
https://www.ncbi.nlm.nih.gov/pubmed/33920895
http://dx.doi.org/10.3390/antibiotics10040442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071314/
https://www.ncbi.nlm.nih.gov/pubmed/33920895
http://dx.doi.org/10.3390/antibiotics10040442

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