Targeting the Sphingosine Kinase/Sphingosine-1-Phosphate Signaling Axis in Drug Discovery for Cancer Therapy

SIMPLE SUMMARY: Cancer is the prime cause of death globally. The altered stimulation of signaling pathways controlled by human kinases has often been observed in various human malignancies. The over-expression of SphK1 (a lipid kinase) and its metabolite S1P have been observed in various types of ca...

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Detalles Bibliográficos
Autores principales: Gupta, Preeti, Taiyab, Aaliya, Hussain, Afzal, Alajmi, Mohamed F., Islam, Asimul, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071327/
https://www.ncbi.nlm.nih.gov/pubmed/33920887
http://dx.doi.org/10.3390/cancers13081898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071327/
https://www.ncbi.nlm.nih.gov/pubmed/33920887
http://dx.doi.org/10.3390/cancers13081898

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