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Differential Regulation of Ca(2+)-Activated Cl(−) Channel TMEM16A Splice Variants by Membrane PI(4,5)P(2)

TMEM16A is a Ca(2+)-activated Cl(−) channel that controls broad cellular processes ranging from mucus secretion to signal transduction and neuronal excitability. Recent studies have reported that membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is an important cofactor that...

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Detalles Bibliográficos
Autores principales: Ko, Woori, Suh, Byung-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071329/
https://www.ncbi.nlm.nih.gov/pubmed/33920953
http://dx.doi.org/10.3390/ijms22084088