Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

SIMPLE SUMMARY: Elevated GLI1 expression levels are associated with improved survival in NB patients and GLI1 overexpression exerts tumor-suppressive traits in cultured NB cells. However, NB cells are protected from increased GLI1 levels as they have lost the ability to form primary cilia and transd...

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Detalles Bibliográficos
Autores principales: Koeniger, Anke, Brichkina, Anna, Nee, Iris, Dempwolff, Lukas, Hupfer, Anna, Galperin, Ilya, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Adhikary, Till, Diederich, Wibke, Lauth, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071409/
https://www.ncbi.nlm.nih.gov/pubmed/33921042
http://dx.doi.org/10.3390/cancers13081908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071409/
https://www.ncbi.nlm.nih.gov/pubmed/33921042
http://dx.doi.org/10.3390/cancers13081908

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