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Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

SIMPLE SUMMARY: Elevated GLI1 expression levels are associated with improved survival in NB patients and GLI1 overexpression exerts tumor-suppressive traits in cultured NB cells. However, NB cells are protected from increased GLI1 levels as they have lost the ability to form primary cilia and transd...

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Detalles Bibliográficos
Autores principales:	Koeniger, Anke, Brichkina, Anna, Nee, Iris, Dempwolff, Lukas, Hupfer, Anna, Galperin, Ilya, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Adhikary, Till, Diederich, Wibke, Lauth, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071409/ https://www.ncbi.nlm.nih.gov/pubmed/33921042 http://dx.doi.org/10.3390/cancers13081908

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