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Histone Epigenetic Signatures in Embryonic Limb Interdigital Cells Fated to Die

During limb formation in vertebrates with free digits, the interdigital mesoderm is eliminated by a massive degeneration process that involves apoptosis and cell senescence. The degradation process is preceded by intense DNA damage in zones located close to methylated DNA, accompanied by the activat...

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Detalles Bibliográficos
Autores principales: Sanchez-Fernandez, Cristina, Lorda-Diez, Carlos I., Duarte-Olivenza, Cristina, Hurle, Juan M., Montero, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071442/
https://www.ncbi.nlm.nih.gov/pubmed/33921015
http://dx.doi.org/10.3390/cells10040911