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Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status

BACKGROUND: Data regarding the inflammatory profile of patients with asthma and chronic rhinosinusitis (CRS-A) with (CRSwNP-A) and without (CRSsNP-A) nasal polyposis remain limited. OBJECTIVE: Define and compare systemic transcriptional changes in patients with CRS-A to those with non-asthma-related...

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Detalles Bibliográficos
Autores principales: Gill, Amarbir S, Pulsipher, Abigail, Sumsion, Jorgen S, Oakley, Gretchen M, Leclair, Laurie W, Howe, Heather, Orlandi, Richard R, Alt, Jeremiah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071779/
https://www.ncbi.nlm.nih.gov/pubmed/33911879
http://dx.doi.org/10.2147/JAA.S301825