How does curvature affect the free-energy barrier of stalk formation? Small vesicles vs apposing, planar membranes

Using molecular simulations of POPC lipids in conjunction with the calculation of the Minimum Free-Energy Path (MFEP), we study the effect of strong membrane curvature on the formation of the first fusion intermediate—the stalk between a vesicle and its periodic image. We find that the thermodynamic...

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Detalles Bibliográficos
Autores principales: Smirnova, Y. G., Müller, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071802/
https://www.ncbi.nlm.nih.gov/pubmed/33547940
http://dx.doi.org/10.1007/s00249-020-01494-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071802/
https://www.ncbi.nlm.nih.gov/pubmed/33547940
http://dx.doi.org/10.1007/s00249-020-01494-1

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