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How does curvature affect the free-energy barrier of stalk formation? Small vesicles vs apposing, planar membranes
Using molecular simulations of POPC lipids in conjunction with the calculation of the Minimum Free-Energy Path (MFEP), we study the effect of strong membrane curvature on the formation of the first fusion intermediate—the stalk between a vesicle and its periodic image. We find that the thermodynamic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071802/ https://www.ncbi.nlm.nih.gov/pubmed/33547940 http://dx.doi.org/10.1007/s00249-020-01494-1 |