Urinary l-erythro-β-hydroxyasparagine—a novel serine racemase inhibitor and substrate of the Zn(2+)-dependent d-serine dehydratase

In the present study, we identified l-erythro-β-hydroxyasparagine (l-β-EHAsn) found abundantly in human urine, as a novel substrate of Zn(2+)-dependent d-serine dehydratase (DSD). l-β-EHAsn is an atypical amino acid present in large amounts in urine but rarely detected in serum or most organs/tissue...

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Detalles Bibliográficos
Autores principales: Ito, Tomokazu, Tono, Mayuka, Kitaura, Yasuyuki, Hemmi, Hisashi, Yoshimura, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071972/
https://www.ncbi.nlm.nih.gov/pubmed/33821987
http://dx.doi.org/10.1042/BSR20210260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071972/
https://www.ncbi.nlm.nih.gov/pubmed/33821987
http://dx.doi.org/10.1042/BSR20210260

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