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Urinary l-erythro-β-hydroxyasparagine—a novel serine racemase inhibitor and substrate of the Zn(2+)-dependent d-serine dehydratase
In the present study, we identified l-erythro-β-hydroxyasparagine (l-β-EHAsn) found abundantly in human urine, as a novel substrate of Zn(2+)-dependent d-serine dehydratase (DSD). l-β-EHAsn is an atypical amino acid present in large amounts in urine but rarely detected in serum or most organs/tissue...
Autores principales: | Ito, Tomokazu, Tono, Mayuka, Kitaura, Yasuyuki, Hemmi, Hisashi, Yoshimura, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071972/ https://www.ncbi.nlm.nih.gov/pubmed/33821987 http://dx.doi.org/10.1042/BSR20210260 |
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