One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2

Limited access to human oligodendrocytes impairs better understanding of oligodendrocyte pathology in myelin diseases. Here, we describe a method to robustly convert human fibroblasts directly into oligodendrocyte-like cells (dc-hiOLs), which allows evaluation of remyelination-promoting compounds an...

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Detalles Bibliográficos
Autores principales: Chanoumidou, Konstantina, Hernández-Rodríguez, Benjamín, Windener, Farina, Thomas, Christian, Stehling, Martin, Mozafari, Sabah, Albrecht, Stefanie, Ottoboni, Linda, Antel, Jack, Kim, Kee-Pyo, Velychko, Sergiy, Cui, Qiao Ling, Xu, Yu Kang T., Martino, Gianvito, Winkler, Jürgen, Schöler, Hans R., Baron-Van Evercooren, Anne, Boespflug-Tanguy, Odile, Vaquerizas, Juan M., Ehrlich, Marc, Kuhlmann, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072064/
https://www.ncbi.nlm.nih.gov/pubmed/33770499
http://dx.doi.org/10.1016/j.stemcr.2021.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072064/
https://www.ncbi.nlm.nih.gov/pubmed/33770499
http://dx.doi.org/10.1016/j.stemcr.2021.03.001

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