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3D Image Analysis of the Complete Ventricular-Subventricular Zone Stem Cell Niche Reveals Significant Vasculature Changes and Progenitor Deficits in Males Versus Females with Aging

With age, neural stem cell (NSC) function in the adult ventricular-subventricular zone (V-SVZ) declines, reducing memory and cognitive function in males; however, the impact on females is not well understood. To obtain a global view of how age and sex impact the mouse V-SVZ, we constructed 3D montag...

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Detalles Bibliográficos
Autores principales: Zhao, Xiuli, Wang, Yue, Wait, Eric, Mankowski, Walt, Bjornsson, Christopher S., Cohen, Andrew R., Zuloaga, Kristen L., Temple, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072131/
https://www.ncbi.nlm.nih.gov/pubmed/33836145
http://dx.doi.org/10.1016/j.stemcr.2021.03.012