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3D Image Analysis of the Complete Ventricular-Subventricular Zone Stem Cell Niche Reveals Significant Vasculature Changes and Progenitor Deficits in Males Versus Females with Aging
With age, neural stem cell (NSC) function in the adult ventricular-subventricular zone (V-SVZ) declines, reducing memory and cognitive function in males; however, the impact on females is not well understood. To obtain a global view of how age and sex impact the mouse V-SVZ, we constructed 3D montag...
Autores principales: | Zhao, Xiuli, Wang, Yue, Wait, Eric, Mankowski, Walt, Bjornsson, Christopher S., Cohen, Andrew R., Zuloaga, Kristen L., Temple, Sally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072131/ https://www.ncbi.nlm.nih.gov/pubmed/33836145 http://dx.doi.org/10.1016/j.stemcr.2021.03.012 |
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