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Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK

Identifying lineage-specific markers is pivotal for understanding developmental processes and developing cell therapies. Here, we investigated the functioning of a cardiomyogenic cell-surface marker, latrophilin-2 (LPHN2), an adhesion G-protein-coupled receptor, in cardiac differentiation. LPHN2 was...

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Detalles Bibliográficos
Autores principales: Lee, Choon-Soo, Cho, Hyun-Jai, Lee, Jin-Woo, Son, HyunJu, Chai, Jinho, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072181/
https://www.ncbi.nlm.nih.gov/pubmed/33798451
http://dx.doi.org/10.1016/j.stemcr.2021.03.003