Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer’s disease

There are currently no disease-modifying treatments for Alzheimer’s disease (AD), and an understanding of preclinical causal biomarkers to help target disease pathogenesis in the earliest phases remains elusive. Here, we investigated whether 19 metabolites previously associated with midlife cognitio...

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Detalles Bibliográficos
Autores principales: Lord, Jodie, Jermy, Bradley, Green, Rebecca, Wong, Andrew, Xu, Jin, Legido-Quigley, Cristina, Dobson, Richard, Richards, Marcus, Proitsi, Petroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072203/
https://www.ncbi.nlm.nih.gov/pubmed/33879569
http://dx.doi.org/10.1073/pnas.2009808118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072203/
https://www.ncbi.nlm.nih.gov/pubmed/33879569
http://dx.doi.org/10.1073/pnas.2009808118

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