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Neutrophil Extracellular Traps in Systemic Lupus Erythematosus Stimulate IgG2 Production From B Lymphocytes

Circulating autoantibodies of IgG2 isotype predominate in Systemic Lupus Erythematosus (SLE) and concur to the development of the renal lesions characteristic of Lupus Nephritis (LN). Anti-dsDNA and anti-histones IgG2, together with anti-podocyte proteins (i.e., α-enolase) are the major autoantibodi...

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Detalles Bibliográficos
Autores principales: Bertelli, Roberta, Schena, Francesca, Antonini, Francesca, Reverberi, Daniele, Signa, Sara, Pedemonte, Nicoletta, Consolaro, Alessandro, Gattorno, Marco, Negrini, Simone, Pupo, Francesca, Volpi, Stefano, Ghiggeri, Gian Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072216/
https://www.ncbi.nlm.nih.gov/pubmed/33912575
http://dx.doi.org/10.3389/fmed.2021.635436