Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma

Sex can be an important determinant of cancer phenotype, and exploring sex-biased tumor biology holds promise for identifying novel therapeutic targets and new approaches to cancer treatment. In an established isogenic murine model of glioblastoma (GBM), we discovered correlated transcriptome-wide s...

Descripción completa

Detalles Bibliográficos
Autores principales: Kfoury, Najla, Qi, Zongtai, Prager, Briana C., Wilkinson, Michael N., Broestl, Lauren, Berrett, Kristopher C., Moudgil, Arnav, Sankararaman, Sumithra, Chen, Xuhua, Gertz, Jason, Rich, Jeremy N., Mitra, Robi D., Rubin, Joshua B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072233/
https://www.ncbi.nlm.nih.gov/pubmed/33850013
http://dx.doi.org/10.1073/pnas.2017148118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072233/
https://www.ncbi.nlm.nih.gov/pubmed/33850013
http://dx.doi.org/10.1073/pnas.2017148118

Ejemplares similares