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Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma

Sex can be an important determinant of cancer phenotype, and exploring sex-biased tumor biology holds promise for identifying novel therapeutic targets and new approaches to cancer treatment. In an established isogenic murine model of glioblastoma (GBM), we discovered correlated transcriptome-wide s...

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Detalles Bibliográficos
Autores principales:	Kfoury, Najla, Qi, Zongtai, Prager, Briana C., Wilkinson, Michael N., Broestl, Lauren, Berrett, Kristopher C., Moudgil, Arnav, Sankararaman, Sumithra, Chen, Xuhua, Gertz, Jason, Rich, Jeremy N., Mitra, Robi D., Rubin, Joshua B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072233/ https://www.ncbi.nlm.nih.gov/pubmed/33850013 http://dx.doi.org/10.1073/pnas.2017148118

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