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Ginkgolide B-induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism induced by Aβ(1-42)

Ginkgolide B (GB), the diterpenoid lactone compound isolated from the extracts of Ginkgo biloba leaves, significantly improves cognitive impairment, but its potential pharmacological effect on astrocytes induced by β-amyloid (Aβ)(1-42) remains to be elucidated. The present study aimed to investigate...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Ding, Yan, Zhuang, Linwu, Wang, Zhenzhong, Xiao, Wei, Zhu, Jingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072312/
https://www.ncbi.nlm.nih.gov/pubmed/33880582
http://dx.doi.org/10.3892/mmr.2021.12096