Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp

Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Consequently, novel therapies are being developed. Ultimately, the impact of compounds on the action potential (AP) needs to be tested in freshly isolated human atrial myocytes. However, the frequent depolarized state of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Verkerk, Arie O., Marchal, Gerard A., Zegers, Jan G., Kawasaki, Makiri, Driessen, Antoine H. G., Remme, Carol Ann, de Groot, Joris R., Wilders, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072333/
https://www.ncbi.nlm.nih.gov/pubmed/33912059
http://dx.doi.org/10.3389/fphar.2021.649414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072333/
https://www.ncbi.nlm.nih.gov/pubmed/33912059
http://dx.doi.org/10.3389/fphar.2021.649414

Ejemplares similares