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3D Cancer Models: The Need for a Complex Stroma, Compartmentalization and Stiffness

The use of tissue-engineered 3D models of cancer has grown in popularity with recent advances in the field of cancer research. 3D models are inherently more biomimetic compared to 2D cell monolayers cultured on tissue-culture plastic. Nevertheless 3D models still lack the cellular and matrix complex...

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Detalles Bibliográficos
Autores principales: Pape, Judith, Emberton, Mark, Cheema, Umber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072339/
https://www.ncbi.nlm.nih.gov/pubmed/33912551
http://dx.doi.org/10.3389/fbioe.2021.660502