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The Cardioprotective Mechanism of Phenylaminoethyl Selenides (PAESe) Against Doxorubicin-Induced Cardiotoxicity Involves Frataxin

Doxorubicin (DOX) is an anthracycline cancer chemotherapeutic that exhibits cumulative dose-limiting cardiotoxicity and limits its clinical utility. DOX treatment results in the development of morbid cardiac hypertrophy that progresses to congestive heart failure and death. Recent evidence suggests...

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Detalles Bibliográficos
Autores principales: Fu, Xiaoyu, Eggert, Mathew, Yoo, Sieun, Patel, Nikhil, Zhong, Juming, Steinke, Ian, Govindarajulu, Manoj, Turumtay, Emine Akyuz, Mouli, Shravanthi, Panizzi, Peter, Beyers, Ronald, Denney, Thomas, Arnold, Robert, Amin, Rajesh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072348/
https://www.ncbi.nlm.nih.gov/pubmed/33912028
http://dx.doi.org/10.3389/fphar.2020.574656