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The Cardioprotective Mechanism of Phenylaminoethyl Selenides (PAESe) Against Doxorubicin-Induced Cardiotoxicity Involves Frataxin
Doxorubicin (DOX) is an anthracycline cancer chemotherapeutic that exhibits cumulative dose-limiting cardiotoxicity and limits its clinical utility. DOX treatment results in the development of morbid cardiac hypertrophy that progresses to congestive heart failure and death. Recent evidence suggests...
Autores principales: | Fu, Xiaoyu, Eggert, Mathew, Yoo, Sieun, Patel, Nikhil, Zhong, Juming, Steinke, Ian, Govindarajulu, Manoj, Turumtay, Emine Akyuz, Mouli, Shravanthi, Panizzi, Peter, Beyers, Ronald, Denney, Thomas, Arnold, Robert, Amin, Rajesh H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072348/ https://www.ncbi.nlm.nih.gov/pubmed/33912028 http://dx.doi.org/10.3389/fphar.2020.574656 |
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