Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution

Humans sweat to cool their bodies and have by far the highest eccrine sweat gland density among primates. Humans’ high eccrine gland density has long been recognized as a hallmark human evolutionary adaptation, but its genetic basis has been unknown. In humans, expression of the Engrailed 1 (EN1) tr...

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Detalles Bibliográficos
Autores principales: Aldea, Daniel, Atsuta, Yuji, Kokalari, Blerina, Schaffner, Stephen F., Prasasya, Rexxi D., Aharoni, Adam, Dingwall, Heather L., Warder, Bailey, Kamberov, Yana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072367/
https://www.ncbi.nlm.nih.gov/pubmed/33850016
http://dx.doi.org/10.1073/pnas.2021722118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072367/
https://www.ncbi.nlm.nih.gov/pubmed/33850016
http://dx.doi.org/10.1073/pnas.2021722118

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