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Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution
Humans sweat to cool their bodies and have by far the highest eccrine sweat gland density among primates. Humans’ high eccrine gland density has long been recognized as a hallmark human evolutionary adaptation, but its genetic basis has been unknown. In humans, expression of the Engrailed 1 (EN1) tr...
Autores principales: | Aldea, Daniel, Atsuta, Yuji, Kokalari, Blerina, Schaffner, Stephen F., Prasasya, Rexxi D., Aharoni, Adam, Dingwall, Heather L., Warder, Bailey, Kamberov, Yana G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072367/ https://www.ncbi.nlm.nih.gov/pubmed/33850016 http://dx.doi.org/10.1073/pnas.2021722118 |
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