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NLRP3 Inflammasome: A Promising Therapeutic Target for Drug-Induced Toxicity

Drug-induced toxicity, which impairs human organ function, is a serious problem during drug development that hinders the clinical use of many marketed drugs, and the underlying mechanisms are complicated. As a sensor of infections and external stimuli, nucleotide-binding oligomerization domain (NOD)...

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Detalles Bibliográficos
Autores principales: Wei, Shanshan, Ma, Wanjun, Zhang, Bikui, Li, Wenqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072389/
https://www.ncbi.nlm.nih.gov/pubmed/33912556
http://dx.doi.org/10.3389/fcell.2021.634607