NLRP3-Inflammasome Inhibition during Respiratory Virus Infection Abrogates Lung Immunopathology and Long-Term Airway Disease Development

Respiratory syncytial virus (RSV) infects most infants by two years of age. It can cause severe disease leading to an increased risk of developing asthma later in life. Previously, our group has shown that RSV infection in mice and infants promotes IL-1β production. Here, we characterized the role o...

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Detalles Bibliográficos
Autores principales: Malinczak, Carrie-Anne, Schuler, Charles F., Duran, Angela J., Rasky, Andrew J., Mire, Mohamed M., Núñez, Gabriel, Lukacs, Nicholas W., Fonseca, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072578/
https://www.ncbi.nlm.nih.gov/pubmed/33923693
http://dx.doi.org/10.3390/v13040692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072578/
https://www.ncbi.nlm.nih.gov/pubmed/33923693
http://dx.doi.org/10.3390/v13040692

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