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NLRP3-Inflammasome Inhibition during Respiratory Virus Infection Abrogates Lung Immunopathology and Long-Term Airway Disease Development
Respiratory syncytial virus (RSV) infects most infants by two years of age. It can cause severe disease leading to an increased risk of developing asthma later in life. Previously, our group has shown that RSV infection in mice and infants promotes IL-1β production. Here, we characterized the role o...
Autores principales: | Malinczak, Carrie-Anne, Schuler, Charles F., Duran, Angela J., Rasky, Andrew J., Mire, Mohamed M., Núñez, Gabriel, Lukacs, Nicholas W., Fonseca, Wendy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072578/ https://www.ncbi.nlm.nih.gov/pubmed/33923693 http://dx.doi.org/10.3390/v13040692 |
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