Predicting Pharmacokinetic Properties of Potential Anticancer Agents via Their Chromatographic Behavior on Different Reversed Phase Materials

The Quantitative Structure-Activity Relationship (QSAR) methodology was used to predict biological properties, i.e., the blood–brain distribution (log BB), fraction unbounded in the brain (f(u,brain)), water-skin permeation (log K(p)), binding to human plasma proteins (log K(a,HSA)), and intestinal...

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Detalles Bibliográficos
Autores principales: Janicka, Małgorzata, Mycka, Anna, Sztanke, Małgorzata, Sztanke, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072580/
https://www.ncbi.nlm.nih.gov/pubmed/33923942
http://dx.doi.org/10.3390/ijms22084257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072580/
https://www.ncbi.nlm.nih.gov/pubmed/33923942
http://dx.doi.org/10.3390/ijms22084257

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