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Chromeno[3,4-b]xanthones as First-in-Class AChE and Aβ Aggregation Dual-Inhibitors

Alzheimer’s disease (AD) is a complex multifactorial disorder, mainly characterized by the progressive loss of memory and cognitive, motor, and functional capacity. The absence of effective therapies available for AD alongside the consecutive failures in the central nervous system (CNS) drug develop...

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Detalles Bibliográficos
Autores principales: Malafaia, Daniela, Oliveira, Ana, Fernandes, Pedro A., Ramos, Maria J., Albuquerque, Hélio M. T., Silva, Artur M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072597/
https://www.ncbi.nlm.nih.gov/pubmed/33923726
http://dx.doi.org/10.3390/ijms22084145