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Chromeno[3,4-b]xanthones as First-in-Class AChE and Aβ Aggregation Dual-Inhibitors
Alzheimer’s disease (AD) is a complex multifactorial disorder, mainly characterized by the progressive loss of memory and cognitive, motor, and functional capacity. The absence of effective therapies available for AD alongside the consecutive failures in the central nervous system (CNS) drug develop...
Autores principales: | Malafaia, Daniela, Oliveira, Ana, Fernandes, Pedro A., Ramos, Maria J., Albuquerque, Hélio M. T., Silva, Artur M. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072597/ https://www.ncbi.nlm.nih.gov/pubmed/33923726 http://dx.doi.org/10.3390/ijms22084145 |
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