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A Heterozygous Mutation in Cardiac Troponin T Promotes Ca(2+) Dysregulation and Adult Cardiomyopathy in Zebrafish

Cardiomyopathies are a group of heterogeneous diseases that affect the muscles of the heart, leading to early morbidity and mortality in young and adults. Genetic forms of cardiomyopathy are caused predominantly by mutations in structural components of the cardiomyocyte sarcomeres, the contractile u...

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Detalles Bibliográficos
Autores principales: Kamel, Sarah M., Koopman, Charlotte D., Kruse, Fabian, Willekers, Sven, Chocron, Sonja, Bakkers, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072640/
https://www.ncbi.nlm.nih.gov/pubmed/33924051
http://dx.doi.org/10.3390/jcdd8040046