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A Heterozygous Mutation in Cardiac Troponin T Promotes Ca(2+) Dysregulation and Adult Cardiomyopathy in Zebrafish
Cardiomyopathies are a group of heterogeneous diseases that affect the muscles of the heart, leading to early morbidity and mortality in young and adults. Genetic forms of cardiomyopathy are caused predominantly by mutations in structural components of the cardiomyocyte sarcomeres, the contractile u...
Autores principales: | Kamel, Sarah M., Koopman, Charlotte D., Kruse, Fabian, Willekers, Sven, Chocron, Sonja, Bakkers, Jeroen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072640/ https://www.ncbi.nlm.nih.gov/pubmed/33924051 http://dx.doi.org/10.3390/jcdd8040046 |
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