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Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects

Addiction to cocaine is associated with dysfunction of the dopamine mesocortical system including impaired dopamine-2 receptor (D2r) signaling. However, the effects of chronic cocaine on neuronal adaptations in this system have not been systematically examined and data available is mostly from males...

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Detalles Bibliográficos
Autores principales: Clare, Kevin, Pan, Chelsea, Kim, Gloria, Park, Kicheon, Zhao, Juan, Volkow, Nora D., Lin, Zhicheng, Du, Congwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072657/
https://www.ncbi.nlm.nih.gov/pubmed/33912043
http://dx.doi.org/10.3389/fphar.2021.624127