A Zinc-Mediated Deprotective Annulation Approach to New Polycyclic Heterocycles

A straightforward approach to new polycyclic heterocycles, 1H-benzo[4,5]imidazo[1,2-c][1,3]oxazin-1-ones, is presented. It is based on the ZnCl(2)-promoted deprotective 6-endo-dig heterocyclization of N-Boc-2-alkynylbenzimidazoles under mild conditions (CH(2)Cl(2), 40 °C for 3 h). The zinc center pl...

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Detalles Bibliográficos
Autores principales: Veltri, Lucia, Amuso, Roberta, Petrilli, Marzia, Cuocci, Corrado, Chiacchio, Maria A., Vitale, Paola, Gabriele, Bartolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072660/
https://www.ncbi.nlm.nih.gov/pubmed/33923572
http://dx.doi.org/10.3390/molecules26082318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072660/
https://www.ncbi.nlm.nih.gov/pubmed/33923572
http://dx.doi.org/10.3390/molecules26082318

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