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A urine-based DNA methylation assay to facilitate early detection and risk stratification of bladder cancer

BACKGROUND: Current non-invasive tests have limited sensitivities and lack capabilities of pre-operative risk stratification for bladder cancer (BC) diagnosis. We aimed to develop and validate a urine-based DNA methylation assay as a clinically feasible test for improving BC detection and enabling p...

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Detalles Bibliográficos
Autores principales: Ruan, Weimei, Chen, Xu, Huang, Ming, Wang, Hong, Chen, Jiaxin, Liang, Zhixin, Zhang, Jingtong, Yu, Yanqi, Chen, Shang, Xu, Shizhong, Hu, Tianliang, Li, Xia, Guo, Yuanjie, Jiang, Zeyu, Chen, Zhiwei, Huang, Jian, Lin, Tianxin, Fan, Jian-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072728/
https://www.ncbi.nlm.nih.gov/pubmed/33902700
http://dx.doi.org/10.1186/s13148-021-01073-x