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Role of α2-Adrenoceptor Subtypes in Suppression of L-Type Ca(2+) Current in Mouse Cardiac Myocytes

Sarcolemmal α2 adrenoceptors (α2-AR), represented by α2A, α2B and α2C isoforms, can safeguard cardiac muscle under sympathoadrenergic surge by governing Ca(2+) handling and contractility of cardiomyocytes. Cardiomyocyte-specific targeting of α2-AR would provide cardiac muscle-delimited stress contro...

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Detalles Bibliográficos
Autores principales: Evdokimovskii, Edward V., Jeon, Ryounghoon, Park, Sungjo, Pimenov, Oleg Y., Alekseev, Alexey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072751/
https://www.ncbi.nlm.nih.gov/pubmed/33923625
http://dx.doi.org/10.3390/ijms22084135