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Role of α2-Adrenoceptor Subtypes in Suppression of L-Type Ca(2+) Current in Mouse Cardiac Myocytes
Sarcolemmal α2 adrenoceptors (α2-AR), represented by α2A, α2B and α2C isoforms, can safeguard cardiac muscle under sympathoadrenergic surge by governing Ca(2+) handling and contractility of cardiomyocytes. Cardiomyocyte-specific targeting of α2-AR would provide cardiac muscle-delimited stress contro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072751/ https://www.ncbi.nlm.nih.gov/pubmed/33923625 http://dx.doi.org/10.3390/ijms22084135 |